Endocrine Abstracts

Background: It is well established that during pregnancy, normal physiological changes occur concomitant with an enhanced metabolic demand for thyroxine/iodine. If dietary iodine intake is sufficient, normal equilibrium is achieved. With deficient iodine intake, the demand not being met, it is believed that pathological alterations occur leading to maternal thyroxineaemia and impaired growth and neurodevelopmental disorders in the offspring. However, there are very few studies...

Ample literature exists on thyroid functioning and adjustments in Iodine-sufficient pregnant women. But information from endemic-iodine zones is meagre. In this study we attempt to understand how the thyroid copes with the dual challenge of iodine deficiency posed by physiological status of pregnancy and that by Iodine-deficient environment.Objective: To compare TSH and FT4 profiles and their mutual correlation in iodine-deficient and iodine-sufficient s...